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Synthesis
DOI: 10.1055/a-2733-1592
DOI: 10.1055/a-2733-1592
Paper
Electrochemically Catalyzed Decarboxylative Borylation of (Hetero)Aryl Carboxylic Acids
Authors
Supported by: National Natural Science Foundation of China 22202021,22372015
Supported by: Changzhou Vocational Institute of Engineering 11130900122004
Funding Information This work was financially supported by National Natural Science Foundation of China (NSFC22202021 and 22372015), the Young Backbone Teachers Fund of Jiangsu Qinglan Project, and the School research fund of Changzhou Vocational Institute of Engineering (11130900122004).
Abstract
A straightforward and efficient electrochemical method for the decarboxylative borylation of (hetero)aryl carboxylic acids has been outlined. This metal-/base-/oxidant-free strategy enables efficient access to arylboronate esters, demonstrating a broad substrate scope (20 examples) with yields of up to 62% while maintaining exceptional atom- and step-economy.
Keywords
Decarboxylation - Borylation - Electrochemical synthesis - Arylboronate esters - Arylcarboxylic acidsPublication History
Received: 30 April 2025
Accepted after revision: 27 October 2025
Accepted Manuscript online:
27 October 2025
Article published online:
14 November 2025
© 2025. Thieme. All rights reserved.
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