Microwave-Assisted Synthesis
and Functionalization of Selenolopyrimidines

Stéphanie Hesse; Célia Chenet; David Thomae; Gilbert Kirsch

doi:10.1055/s-0028-1088006

PAPER

Microwave-Assisted Synthesis and Functionalization of Selenolopyrimidines

Stéphanie Hesse*, Célia Chenet, David Thomae, Gilbert Kirsch
Laboratoire d’Ingénierie Moléculaire et Biochimie Pharmacologique, Institut Jean Barriol FR CNRS 2843, Université Paul Verlaine-Metz, 1 Boulevard Arago, 57070 Metz, France
Fax: +33(3)87315801; e-Mail: hesse@univ-metz.fr;

Abstract

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Abstract

Microwave-assisted synthesis allowed efficient access to 4-chloroselenolo[3,2-d]pyrimidines in short times and very good yields. Some functionalizations by S_NAr and palladium-catalyzed reactions are also reported.

Key words

selenium - pyrimidines - heterocycles - cyclizations - microwave-assisted reactions

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References

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