Eur J Pediatr Surg 2009; 19(6): 405-407
DOI: 10.1055/s-0029-1202251
Case Gallery

© Georg Thieme Verlag KG Stuttgart · New York

Neonatal Gastrointestinal Mucormycosis Clinically Mimicking Necrotizing Enterocolitis

D. Jain 1 , K. Kohli 1
  • 1Department of Pathology, Maulana Azad Medical College, New Delhi, India
Further Information

Publication History

Publication Date:
30 April 2009 (online)

Introduction

Mucormycosis is a rare opportunistic fungal infection with a frequently fatal outcome [12]. One third of patients with gastrointestinal mucormycosis were diagnosed as necrotizing enterocolitis (NEC) preoperatively [7]. However; a few cases with intestinal obstruction have also been reported so far [6]. We report a case of neonatal mucormycosis/zygomycosis diagnosed following laparotomy and resection for presumptive NEC.

References

  • 1 Agarwal K, Sharma M, Singh S, Jain M. Antemortem diagnosis of gastrointestinal mucormycosis in neonates: report of two cases and review of literature. Indian.  J Pathol Microbiol. 2006;  49 430-432
  • 2 Alexander P, Alladi A, Correa M, D’Cruz AJ. Neonatal colonic mucormycosis – a tropical perspective.  J Trop Pediatr. 2005;  51 54-59
  • 3 Budhiraja S, Sood N, Singla S, Gupta V. Gastrointestinal mucormycosis in a neonate: Survival without antifungal therapy.  Indian J Gastroenterol. 2007;  26 198
  • 4 Calle S, Klatsky S. Intestinal phycomycosis (mucormycosis).  Am J Clin Pathol. 1966;  45 264-272
  • 5 Dhingra KK, Mandal S, Khurana N. Unsuspected intestinal mucormycosis in a neonate presenting as necrotizing enterocolitis (NEC).  Eur J Pediatr Surg. 2008;  18 119-120
  • 6 Gulati S, Barthakur G, Banerjee CK, Singhi S. Zygomycosis of the colon.  Ind Pediatr. 1991;  28 940-943
  • 7 Kataria R, Gupta DK, Mitra DK. Colonic mucormycosis in a neonate.  Pediatric Surgery International. 1995;  10 271-273
  • 8 Krick JA, Remington JS. Opportunistic invasive fungal infection in patients with leukemia and lymphoma.  Clin Haematol. 1976;  5 249-310
  • 9 Lee JH, Ha HK, Yoo E, Yang SK, Min YI, Auh YH. CT and sonographically guided biopsy in a patient with intestinal mucormycosis.  AJR. 2000;  175 129-131
  • 10 Madhavan M, Reddy DJ. Mucormycosis of intestine. Indian.  J Pathol Bacteriol. 1969;  12 46-48
  • 11 Michalak DM, Cooney DR, Rhodes KH, Telander RL, Kleinberg F. Gastrointestinal mucormycosis in infants and children. A cause of intestinal cellulitis and perforation.  J Pediatr Surg. 1980;  15 320-324
  • 12 Sharma MC, Gill SS, Kashyapn S, Kataria R, Gupta DK, Sahni P, Acharya SK. Gastrointestinal mucormycosis – an uncommon isolated mucormycosis.  Indian J Gastroenterol. 1998;  17 131-133
  • 13 Sridhar S, Jana AK, Thomas S, Solomon R. Mucormycosis of the neonatal gastrointestinal tract.  Indian Pediatr. 2001;  38 294-297
  • 14 Thompson SR, Bade PG, Tams M, Chrystal V. Gastrointestinal mucormycosis.  Br J Surg. 1991;  78 952-954
  • 15 Woodward A, McTigue C, Hogg C, Watkins A, Tan H. Mucormycosis of the neonatal gut: a ‘new’ disease or a variant of necrotizing enterocolitis?.  J Pediatr Surg. 1992;  27 737-740

Correspondence

Dr. D. Jain

Department of Pathology

Maulana Azad Medical College

Bhadhur Shah Zafar Marg

110002 New Delhi

India

Phone: +91/986/889 51 12

Fax: +91/011/2323 55 74

Email: deepalijain76@gmail.com

    >