Palladium-Catalyzed
Cross-Coupling Reaction of AlArEt2(THF) with Aryl Bromides

Wan-Ting Shu; Shuangliu Zhou; Han-Mou Gau

doi:10.1055/s-0029-1217032

FEATUREARTICLE

Palladium-Catalyzed Cross-Coupling Reaction of AlArEt₂(THF) with Aryl Bromides

Wan-Ting Shu^a, Shuangliu Zhou^a,b, Han-Mou Gau*^a
^a Department of Chemistry, National Chung Hsing University, Taichung 402, Taiwan
Fax: +886(4)22862547; e-Mail: hmgau@dragon.nchu.edu.tw;
^b Anhui Key Laboratory of Molecule-based Materials, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241000, P. R. of China

Abstract

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Abstract

Efficient cross-coupling reactions of aryl bromides with AlArEt₂(THF) (Ar = Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-Me₃SiC₆H₄, or 2-naphthyl) catalyzed by a catalytic system of 1 mol% Pd(OAc)₂ and 2 mol% PCy₃ furnish aryl-aryl coupling products. The system works well for a wide range of aryl bromides regardless of the electronic or steric nature of the substituent on the aryl bromides.

Key words

cross-coupling - palladium - aryl - aluminum - biaryl

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References

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Palladium-Catalyzed Cross-Coupling Reaction of AlArEt2(THF) with Aryl Bromides

Palladium-Catalyzed Cross-Coupling Reaction of AlArEt₂(THF) with Aryl Bromides