Hydrogenation of β-N-Substituted
and β-N,N-Disubstituted Enamino Esters in the Presence
of Iridium(I) Catalyst

Hania Hebbache; Zakia Hank; Christian Bruneau; Jean-Luc Renaud

doi:10.1055/s-0029-1217405

PAPER

Hydrogenation of β-N-Substituted and β-N,N-Disubstituted Enamino Esters in the Presence of Iridium(I) Catalyst

Hania Hebbache^a,b, Zakia Hank^a, Christian Bruneau*^b, Jean-Luc Renaud*^c
^a Laboratoire d’Électrochimie-Corrosion, Métallurgie et Chimie Minérale, Université des Sciences et Technologies Houari Boumedienne, Faculté de Chimie, BP32 El Alia 16111 Bab-Ezzouar, Alger, Algérie
^b UMR 6226, CNRS-Université de Rennes 1, Sciences Chimiques de Rennes, Catalyse et Organométalliques, Campus de Beaulieu, 35042 Rennes Cedex, France
Fax: +33(2)23236939; e-Mail: christian.bruneau@univ-rennes1.fr;
^c Laboratoire de Chimie Moléculaire et Thioorganique, UMR 6507, INC3M, FR 3038, ENSICAEN-Université de Caen, 14050 Caen, France
Fax: 33(2)31452877; e-Mail: jean-luc.renaud@ensicaen.fr;

Abstract

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Abstract

Several new β-amino esters were prepared in two simple steps from β-keto ester derivatives and primary and secondary amines under mild conditions. The hydrogenation of various enamino esters was performed at 50 ˚C in the presence of iridium catalysts. The new β-N-substituted amino esters were isolated in high yields.

Key words

catalysis - hydrogenation - iridium - β-amino esters

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References

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