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Synfacts 2009(12): 1398-1398  
DOI: 10.1055/s-0029-1218207
Organo- and Biocatalysis
© Georg Thieme Verlag Stuttgart ˙ New York

Brønsted Acid Catalyzed Alkylation of Enamides

Contributor(s): Benjamin List, Anna Lee
Q.-X. Guo*, Y.-G. Peng, J.-W. Zhang, L. Song, Z. Feng, L.-Z. Gong*
Southwest University, Chongqing and University of Science and Technology of China, Hefei, P. R. of China
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Publication History

Publication Date:
20 November 2009 (online)

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Significance

The authors report the enantioselective alkylation of enamides with indoyl alcohols using chiral phosphoric acid catalysts. The reactions provided β-indolyl ketones in high yields and good enantioselectivities.