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Synfacts 2010(1): 0004-0004
DOI: 10.1055/s-0029-1218401
DOI: 10.1055/s-0029-1218401
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Antibiotic TAN-1085
K. Mori, K. Ohmori, K. Suzuki*
Tokyo Institute of Technology, Japan
Further Information
Publication History
Publication Date:
21 December 2009 (online)
Significance
The synthesis of TAN-1085 by Suzuki and co-workers is notable for its consecutive relay of central and axial chirality elements in three chirality transfer steps: central → axial (A + B → C), axial → axial (F → G) and axial → central (H → I).