Synthesis 2010(6): 908-910  
DOI: 10.1055/s-0029-1218643
SHORTPAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Efficient Copper-Catalyzed N-Arylation of Amides and Imidazoles with Aryl Iodides

Md. Ashif Ali, Prasenjit Saha, Tharmalingam Punniyamurthy*
Department of Chemistry, Indian Institute of Technology, Guwahati 781039, India
Fax: +91(361)2690762; e-Mail: tpunni@iitg.ernet.in;
Further Information

Publication History

Received 22 October 2009
Publication Date:
08 January 2010 (online)

Abstract

The C-N cross-coupling of amides and imidazoles with aryl iodides is described using CuI in tetrabutylammonium bromide (TBAB) under ligand-free conditions. The reaction is simple, general, and efficient affording the C-N cross-coupled products in shorter time and in high yield.

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