A Simple and Efficient Method for the Three-Component Synthesis of Homoallylic Amines Catalyzed by Indium Triflate

Abstract

Indium triflate catalyzes efficiently the one-pot three-component condensation of aldehydes, amines, and allyltributylstannane to afford the corresponding products of homoallylic amines in excellent yields at room temperature. All reactions were carried out using the catalyst in 10 mol%. This methodology was successfully applied to a variety of aldehydes and amines.

Key words

aldehydes - amines - allyltributylstannane - indium triflate - homoallylic amines

References

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