Simple Selective Synthesis of
2,4- and 2,6-Diarylpyridines through Metal-Free Cyclocondensation
of Aromatic Ketones with Ammonium Acetate

Jin Liu; Chuanxin Wang; Liansheng Wu; Fen Liang; Guosheng Huang

doi:10.1055/s-0030-1258274

PAPER

Simple Selective Synthesis of 2,4- and 2,6-Diarylpyridines through Metal-Free Cyclocondensation of Aromatic Ketones with Ammonium Acetate

Jin Liu, Chuanxin Wang, Liansheng Wu, Fen Liang, Guosheng Huang*
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. of China
Fax: +86(931)8912582; e-Mail: hgs2368@163.com;

Abstract

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Abstract

A simple and selective one-pot synthesis of 2,4- and 2,6-diarylpyridines through the cyclocondensation reaction of aromatic ketones with ammonium acetate has been developed. The procedure is metal-free, convenient, and efficient, and the substrates are readily available.

Key words

diarylpyridines - selective - cyclocondensation - aromatic ketones - ammonium acetate

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References

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