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Synthesis 2010(24): 4188-4192  
DOI: 10.1055/s-0030-1258287
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Samarium-Promoted Michael Addition between Aroyl Chlorides and Chalcones

Yongjun Liu, Yuanying Li, Yan Qi, Jun Wan*
State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. of China
Fax: +86(532)84023927; e-Mail: wanjundz@sohu.com;
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Publication History

Received 26 July 2010
Publication Date:
07 October 2010 (online)

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Abstract

A novel Michael addition type reaction between aroyl chlorides and chalcones was realized in the presence of samarium metal when N,N-dimethylformamide was used as a solvent. A variety of 1,4-diketones were thereby synthesized in moderate to good yields. The possible mechanism is also discussed.

Key words

samarium - Michael addition - aroyl chlorides - chalcones - 1,4-diketones

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