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Synfacts 2011(7): 0758-0758  
DOI: 10.1055/s-0030-1260638
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Enantioselective Hydroxyamination Reaction for 3-Hydroxyamino-2-Oxindoles

Contributor(s): Mark Lautens, Patrick T. Franke
K. Shen, X. Liu, G. Wang, L. Lin, X. Feng*
Sichuan University, Chengdu, P. R. of China
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Publication History

Publication Date:
17 June 2011 (online)

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Significance

A highly efficient enantioselective hydroxyamination of N-unprotected 3-substituted 2-oxindoles has been developed. The products are obtained in excellent enantioselectivities up to 98%.