Limonoids and Diterpenoids from Toona ciliata Roem. var. yunnanensis

Abstract

Three new limonoids (toonaciliatins N−P, 1–3) and four new pimaradiene-type diterpenoids (toonacilidins A–D, 4–7) were isolated from the leaves and twigs of Toona ciliata Roem. var. yunnanensis. Their structures were elucidated on the basis of spectroscopic methods. Toonacilidin B (5) showed moderate inhibitory activity against H. pylori-SS1 with an MIC of 50 µg/mL.

Key words

Toona ciliata Roem. var. yunnanensis – Meliaceae - limonoid - diterpenoid - antimicrobial assay

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