Incomptines C and D, Two Heliangolides from Decachaeta incompta and Their Antiprotozoal Activity

Abstract

Two new heliangolides, incomptines C (3) and D (4), were isolated from the leaves of Decachaeta incompta. The structures were established by spectroscopic methods and confirmed by X-ray crystallography. The antiprotozoal activity of incomptines C and D was evaluated. Additionally, the chromatographic profile of the leaves and roots extracts were compared to identify incomptines A–D (1–4) in each extract.

Key words

Asteraceae - Decachaeta incompta - Giardia lamblia - Entamoeba histolytica - heliangolides - antiprotozoal activity

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