Direct Noncatalytic Electrophilic Trifluoroacetylation of Electron-Rich Pyrazoles

Abstract

Electron-rich N-substituted pyrazoles smoothly reacted with trifluoroacetic anhydride in pyridine to form the corresponding trifluoromethyl ketones in good yields.

Key words

trifluoromethyl group - trifluoroacetyl group - fluorine - pyrazole - building blocks

• References

• 1 These authors contributed equally to this work.

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