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Eur J Pediatr Surg 2013; 23(03): 219-225
DOI: 10.1055/s-0033-1347912
Review
Georg Thieme Verlag KG Stuttgart · New York

Long-Term Outcome of Esophageal Anastomosis

R. J. Rintala
1   Department of Pediatric Surgery, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland
,
M. P. Pakarinen
1   Department of Pediatric Surgery, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland
› Author Affiliations
Further Information

Publication History

23 April 2013

23 April 2013

Publication Date:
04 June 2013 (online)

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Abstract

After repair of esophageal atresia (EA) in a newborn, esophageal dysmotility presenting as dysphagia and symptomatic gastroesophageal reflux are common. Significant esophageal morbidity associated with EA extends into adulthood. In adulthood approximately one-fifth of the patients have developed epithelial metaplastic changes, one-third of these have intestinal metaplasia (Barrett esophagus). Surgical complications, increasing age, and impaired esophageal motility predict the development of epithelial metaplasia after repair of EA. To date, worldwide, eight cases of esophageal cancer have been reported in young adults treated for EA. Incidence of esophageal cancer after EA repair is very much likely to increase in the future. Life-long endoscopic follow-up is warranted in patients with EA.

Keywords

esophageal atresia - long-term outcomes
 

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