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Planta Med 2013; 79(18): 1762-1766
DOI: 10.1055/s-0033-1351044
Natural Product Chemistry
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Alienusolin, a New 4α-Deoxyphorbol Ester Derivative, and Crotonimide C, a New Glutarimide Alkaloid from the Kenyan Croton alienus

Beth Ndunda
1   Department of Chemistry, Nairobi University, Nairobi, Kenya
,
Moses K. Langat
2   Department of Chemistry, FEPS, University of Surrey, Guildford, Surrey, United Kingdom
,
John M. Wanjohi
1   Department of Chemistry, Nairobi University, Nairobi, Kenya
,
Jacob O. Midiwo
1   Department of Chemistry, Nairobi University, Nairobi, Kenya
,
Leonidah O. Kerubo
1   Department of Chemistry, Nairobi University, Nairobi, Kenya
› Author Affiliations
Further Information

Publication History

received 23 May 2013
revised 14 July 2013

accepted 13 October 2013

Publication Date:
19 December 2013 (online)

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Abstract

Two novel compounds, alienusolin, a 4α-deoxyphorbol ester (1), crotonimide C, a glutarimide alkaloid derivative (2), and ten known compounds, julocrotine (3), crotepoxide (4), monodeacetyl crotepoxide (5), dideacetylcrotepoxide, (6), β-senepoxide (7), α-senepoxide (8), (+)-(2S,3R-diacetoxy-1-benzoyloxymethylenecyclohex-4,6-diene (9), benzyl benzoate (10), acetyl aleuritolic (11), and 24-ethylcholesta-4,22-dien-3-one (12) were isolated from the Kenyan Croton alienus. The structures of the compounds were determined using NMR, GCMS, and HRESIMS studies.

Key words

4α-deoxyphorbol ester - glutarimide alkaloid - Croton alienus - Euphorbiaceae

Supporting Information

 

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