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Planta Med 2014; 80(07): 583-589
DOI: 10.1055/s-0034-1368353
DOI: 10.1055/s-0034-1368353
Natural Product Chemistry
Original Papers
Anti-inflammatory Terpenes from Flowers of Inula japonica
Authors
Further Information
Publication History
received 16 October 2013
revised 21 January 2014
accepted 10 March 2014
Publication Date:
07 April 2014 (online)
Abstract
Five new terpenes (1–5) and ten known compounds (6–15) were isolated from Inula japonica, and their structures were identified by spectroscopic analysis. Compounds 3 and 14 showed positive inhibitory effects on nitric oxide production. Furthermore, compound 14 suppressed both leukotriene C4 synthesis and degranulation in c-kit ligand-induced bone marrow-derived mast cells.
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