Synthesis of Uracil-, Coumarin- and Quinolone-Fused Benzosultams and Benzosultones

Abstract

An efficient method for the regioselective synthesis of uracil-, coumarin- and quinolone-fused benzosultams and benzosultones is reported. The method offers a synthetic route to highly functionalized sultam and sultone derivatives in 75–95% yield under mild conditions. Density functional theory studies have been used to explain the regio­selectivity in the synthesis of the coumarin- and quinolone-fused sultams and sultones.

Key words

sultams - sultones - regioselectivity - density functional theory

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