A Convenient Method for Catalytic Aromatic Pentafluoroethylation Using Potassium (Pentafluoroethyl)trimethoxyborate

Abstract

A method for the copper-catalyzed pentafluoroethylation of aryl iodides using potassium (pentafluoroethyl)trimethoxyborate has been developed. The borate was found to be a convenient pentafluoroethyl source. In parallel, it was found that the solvent, as well as ligand, makes significant impact on the catalytic perfluoroalkylations.

Key words

fluorine - copper - cross-coupling - pentafluoroethylation - boron

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