One-Step O-Demethyl-Decarboxylation of ortho-Methoxy Aromatic Carboxylic Acids

Abstract

A highly selective decarboxydemethylation of o-methoxyarenecarboxylic acids is described. The reaction takes place in DMPU at 170 °C in the presence of TMEDA and iron powder. A similar reaction has not been reported until now.

Key words

ether C–O cleavage - decarboxylation - aryl methyl ethers - phenols - iron catalysis

• References


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