Regio- and Stereoselective Palladium-Catalyzed Intermolecular Three-Component Aryletherification of Terminal Allenes

Xin-Xing Wu; Chenjun Wang; Wanrong Zhao; Haiying Zhao; Shufeng Chen

doi:10.1055/s-0037-1610534

Synthesis, Table of Contents

Synthesis 2018; 50(20): 4097-4103
DOI: 10.1055/s-0037-1610534

paper

Regio- and Stereoselective Palladium-Catalyzed Intermolecular Three-Component Aryletherification of Terminal Allenes

Authors

Xin-Xing Wu

Inner Mongolia Key Laboratory of Fine Organic Synthesis, Department of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, P. R. of China Email: shufengchen@imu.edu.cn
Chenjun Wang

Inner Mongolia Key Laboratory of Fine Organic Synthesis, Department of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, P. R. of China Email: shufengchen@imu.edu.cn
Wanrong Zhao

Inner Mongolia Key Laboratory of Fine Organic Synthesis, Department of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, P. R. of China Email: shufengchen@imu.edu.cn
Haiying Zhao

Inner Mongolia Key Laboratory of Fine Organic Synthesis, Department of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, P. R. of China Email: shufengchen@imu.edu.cn
Shufeng Chen *

Inner Mongolia Key Laboratory of Fine Organic Synthesis, Department of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, P. R. of China Email: shufengchen@imu.edu.cn

Abstract

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Abstract

A palladium-catalyzed three-component intermolecular aryletherification reaction of ferrocene-substituted allenes, aryl iodides and phenols or alcohols is reported. In this three-component reaction, two new C–C and C–O bonds are formed in one step with high regio- and stereoselectivity. The high selectivity obtained in this reaction can be attributed to the steric effect of the bulky ferrocene group.

Key words

aryletherification - allenes - palladium - stereoselectivity - intermolecular three-component reaction

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References

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Supplementary Material

Supporting Information (PDF)