Synthesis, Table of Contents Synthesis 2020; 52(12): 1833-1840DOI: 10.1055/s-0039-1691740 paper © Georg Thieme Verlag Stuttgart · New YorkSynthesis of 2,4-Diarylquinoline Derivatives via Chloranil-Promoted Oxidative Annulation and One-Pot Reaction Authors Author Affiliations Dongping Cheng∗ a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China Xianhang Yan a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China Jing Shen a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China Yueqi Pu a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China Xiaoliang Xu∗ b College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. of China Email: chengdp@zjut.edu.cn Jizhong Yan∗ a College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. of China Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) Abstract An oxidative annulation for the synthesis of 2,4-diarylquinolines from o-allylanilines is disclosed that uses recyclable reagent Chloranil as the oxidant. The corresponding products are obtained in moderate to excellent yields. Furthermore, a one-pot access to 2,4-diarylquinolines from easily available anilines and 1,3-diarylpropenes is described as a highly atom-efficient protocol that involves oxidative coupling, rearrangement, and oxidative annulation. Key words Key wordsoxidative annulation - one-pot reaction - chloranil - 2,4-diarylqunoline Full Text References References 1 Chen YL, Fang KC, Sheu JY, Hsu SL, Tzeng CC. J. Med. Chem. 2001; 44: 2374 2 Kaur K, Jain M, Reddy RP, Jain R. Eur. J. Med. Chem. 2010; 45: 3245 3 Praveen C, DheenKumar P, Muralidharan D, Perumal PT. Bioorg. Med. Chem. Lett. 2010; 20: 7292 4 Mukherjee S, Pal M. 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