Abstract
Objective To estimate the incidence of adverse pregnancy outcomes in women with incidentally
detected unicornuate uteri.
Study Design This is a descriptive study. Database review identified patients with unicornuate
uteri and singleton pregnancies at ≥12 weeks' gestation. Patients were excluded if
the diagnosis of unicornuate uterus was made after a midtrimester loss or preterm
delivery. Records were reviewed to obtain clinical outcomes. Chi-square test, Fisher's
exact test, and Mann–Whitney U-test were used for statistical analysis.
Results Forty patients with 67 pregnancies were included. Most diagnoses were made during
infertility work-up (76.2%). There was one midtrimester loss (1.5%). In the remaining
66 pregnancies, median gestational age at delivery was 38 weeks. There were 20 (30.3%)
preterm births, 9 (13.6%) spontaneous preterm births, and 11 (16.7%) indicated preterm
births. Women with indicated preterm births were more likely to have placental abnormalities.
Of the available placental pathology, 45.2% had histological lesions of malperfusion.
Cesarean delivery was performed in 77.3% of cases.
Conclusion Most women with incidentally detected unicornuate uteri gave birth at term. More
than half the preterm births were indicated, with relatively high rates of placental
abnormalities. In patients without a poor obstetrical history, rates of midtrimester
loss and spontaneous preterm birth were lower than previously described.
Keywords
congenital uterine anomaly - incidental - lesions of malperfusion - Mullerian duct
anomaly - placental abnormality - pregnancy outcomes - unicornuate uterus
