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Am J Perinatol 2021; 38(02): 145-149
DOI: 10.1055/s-0039-1695012
Original Article

Systemic to Pulmonary Collaterals in Extremely Low Birth Weight Infants: Incidence, Clinical Significance, and Hemodynamic Features

Cynthia Hayek
1   Division of Neonatal Medicine, LAC + USC Medical Center, Los Angeles, California
2   Division of Neonatal Medicine, Center for Fetal and Neonatal Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California
,
Rowena Cayabyab
1   Division of Neonatal Medicine, LAC + USC Medical Center, Los Angeles, California
,
Ima Thompson
1   Division of Neonatal Medicine, LAC + USC Medical Center, Los Angeles, California
2   Division of Neonatal Medicine, Center for Fetal and Neonatal Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California
,
Mahmood Ebrahimi
1   Division of Neonatal Medicine, LAC + USC Medical Center, Los Angeles, California
,
Bijan Siassi
1   Division of Neonatal Medicine, LAC + USC Medical Center, Los Angeles, California
,
Rangasamy Ramanathan
1   Division of Neonatal Medicine, LAC + USC Medical Center, Los Angeles, California
2   Division of Neonatal Medicine, Center for Fetal and Neonatal Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California
› Author Affiliations Funding None.
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Abstract

Objective This study aimed to determine the incidence of systemic to pulmonary collaterals (SPCs) in extremely low birth weight infants and to assess its clinical and hemodynamic significance beyond the neonatal period.

Study Design Retrospective cohort study was conducted on 61 infants with echocardiogram performed at the time of discharge to determine the presence of SPC and to measure the right and left ventricular outputs and left atrium to aortic ratio. We compared two groups: small or no SPC (Group 1) to moderate or large SPC (Group 2) on demographics, clinical outcomes, and echocardiographic parameters.

Results Sixty-one infants were included. The incidence of SPC was 57%; 21% of infants had moderate or large shunts and 31% had small SPC. Demographics, clinical outcomes, and echocardiographic parameters were not significantly different between small or no SPC and moderate to large SPC.

Conclusion More than half of the infants had SPC. The size of the shunt did not affect the clinical outcomes nor the echocardiographic parameters measured. All infants had cardiac output above the normative mean.

Keywords

systemic to pulmonary collateral - extremely low birth weight - echocardiogram - very low birth weight - patent ductus arteriosus


Publication History

Received: 11 February 2019

Accepted: 11 July 2019

Article published online:
20 August 2019

© 2019. Thieme. All rights reserved.

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