Due to a growing interest in aza-fused polyaromatic systems among various sciences,
enormous attention has been continuously paid to design and synthesize novel chemotypes
of N-fused heterocycles. During the course of continued efforts in this line, it was
found that divergent access to new polycyclic N-fused heteroaromatics was enabled by choice of reaction solvent. Described herein
are solvent-controlled selective approaches to three novel N-fused azacycles, benzo-[d]imidazole-pyrrolo[1,2-a]pyrazine hybrids, under mild conditions. The plausible reaction mechanism for each
class of compound is suggested as well.
Key words
polycyclic heteroaromatics - hybrid structure - benzo[
d]-imidazole - pyrrolo[1,2-
a]pyrazine - chemical space - diversity-oriented synthesis - atom-economy - fluorescence
