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J Pediatr Intensive Care 2021; 10(01): 038-044
DOI: 10.1055/s-0040-1713436
Original Article

Exploration of Sepsis-Associated Coagulopathy Severity and Pediatric Septic Shock Outcomes

Jeremy M. Loberger
1   Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, United States
,
Inmaculada B. Aban
2   Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States
,
Priya Prabhakaran
1   Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, United States
› Author Affiliations Funding None.
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Abstract

The objective of this study was to explore correlations between sepsis-associated coagulopathy (SAC) in pediatric septic shock and clinical outcomes. This was a retrospective cohort study of all children admitted to a single, academic pediatric intensive care unit with septic shock over 6 years. The prevalence of SAC was 93.5% with 61% being severe. Those with severe SAC were more likely to have a positive blood culture and have longer median duration of ventilation. All observed mortalities occurred in the severe SAC and indeterminate SAC groups. SAC is highly prevalent in pediatric septic shock and may predict important outcomes.

Keywords

septic shock - disseminated intravascular coagulation - PICU

Note

This study was presented as an oral abstract presentation at the 2018 Society of Critical Care Medicine Congress and published in electronic abstract form only following that meeting.




Publication History

Received: 06 April 2020

Accepted: 07 May 2020

Article published online:
26 June 2020

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