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Journal of Pediatric Epilepsy 2021; 10(03): 110-116
DOI: 10.1055/s-0040-1713907
Original Article

Electrocardiography Parameters Changes in Epilepsy and Febrile Convulsion Children Compared with Controls

Noor Mohammad Noori 
1   Children & Adolescent Health Research Center, School of Medicine, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran
,
Alireza Teimouri 
1   Children & Adolescent Health Research Center, School of Medicine, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran
,
Ali Khajeh 
1   Children & Adolescent Health Research Center, School of Medicine, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran
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Abstract

Epilepsy and febrile convulsion are the most common neurological diseases with significant effect on cardiac functions. This study aimed to evaluate electrocardiography parameters alterations in epilepsy and febrile convulsion children compared with controls. In this comparison study, 270 children analyzed who shared equally in epilepsy, febrile convulsion, and healthy that aged from 0.5 to 5 years. The participants were collected from Ali ibn Abi Talib Hospital of Zahedan, Iran. Epilepsy confirmed based on definition of having at least two unprovoked seizures in 24 hours. Febrile convulsion was confirmed based on its definition by the International League against Epilepsy. Healthy children selected from those referred to the hospital with fever and without any underline diseases. Electrocardiography was performed by a pediatric cardiologist. Data were analyzed using SPSS 19 with p < 0.05 significant level. Heart rate was higher in epilepsy (129.64 ± 27.63) compared with control (108.78 ± 26.01) and febrile convulsion (125.79 ± 25.38; X 2 = 28.701, p < 0.001). S wave in lead V1 was higher in controls (0.72 ± 0.36) compared with epilepsy (0.58 ± 0.45) and febrile convulsion (0.58 ± 0.36). QT dispersion and QTc dispersion levels were higher in epilepsy than febrile convulsion children that both were higher than controls. Concluded that R in aVL, LV mass (LVM), QT dispersion, and QTc dispersion were higher significantly in epilepsy compared with febrile convulsion children. To maintain a good strategic treatment in patients with epilepsy and febrile convulsion, there is a need to assess alternations in ECG parameters, especially QT interval changes that lead to better comprehensive autonomic changes.

Keywords

electrocardiography - epilepsy - febrile convulsion - children

Ethical Approval

Consent form was obtained from the participants or their guardians after the study approval. The study was approved as a resident thesis (ID-code: 945) by the Ethics Committee of Zahedan University of Medical Sciences, Zahedan, Iran.




Publication History

Received: 17 March 2020

Accepted: 30 May 2020

Article published online:
08 July 2020

© 2021. Thieme. All rights reserved.

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