Am J Perinatol 2022; 39(10): 1055-1064
DOI: 10.1055/s-0040-1721694
Review Article

Maternal Cardiovascular Function Following a Pregnancy Complicated by Preeclampsia

Authors

  • Logan C. Barr

    1   Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada
  • Kiera Liblik

    2   Cardiovascular Imaging Network at Queen's, Department of Medicine, Queen's University, Kingston, Ontario, Canada
  • Amer M. Johri

    2   Cardiovascular Imaging Network at Queen's, Department of Medicine, Queen's University, Kingston, Ontario, Canada
  • Graeme N. Smith

    1   Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada
Preview

Abstract

Preeclampsia is a hypertensive pregnancy complication with an unknown etiology and high maternal burden worldwide. Burgeoning research has linked preeclampsia to adverse maternal health outcomes remote from pregnancy; however, the intermediary mechanisms responsible for this association have not been sufficiently established. In the present narrative review, we summarize leading evidence of structural and functional cardiovascular changes associated with prior preeclampsia, and how these changes may be linked to future maternal disease.

Key Points

  • Prior preeclampsia is associated with subclinical structural and functional vascular changes remote from pregnancy.

  • Maternal cardiac adaptations to preeclampsia may have long-term implications on cardiovascular health.

  • Clinicians have an opportunity to minimize maternal disease risk following preeclampsia.



Publikationsverlauf

Eingereicht: 11. Juli 2020

Angenommen: 04. November 2020

Artikel online veröffentlicht:
15. Dezember 2020

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