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Synfacts 2024; 20(06): 0646
DOI: 10.1055/s-0043-1773290
Innovative Drug Discovery and Development

[3+2] Cycloaddition Approach to Difluoromethyl Isoxazoline Derivatives

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    Contributor(s):

  • Antonia F. Stepan (Roche)

  • Seong Heon Kim (Hyundai Pharm)

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Key words

difluoromethylation - isoxazolines - [3+2] cycloaddition - spirocycles - late-stage functionalization - building blocks


Publication History

Article published online:
14 May 2024

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