Planta Med 2023; 89(14): 1325-1326
DOI: 10.1055/s-0043-1773964
Abstracts
Monday 3rd July 2023 | Poster Session I
Phytochemistry I – General

Medicinal Centauri Honey: a promising ingredient?

Márcia Santos Filipe
1   CBIOS – Universidade Lusófona’s Research Center for Biosciences & Health Technologies, Campo Grande 376, 1749-024 Lisbon, Portugal
2   Universidad de Alcalá de Henares. Facultad de Farmacia, Departamento de Ciencias Biomédicas (Área de Farmacología; Nuevos agentes antitumorales, Acción tóxica sobre células leucémicas. Ctra. Madrid-Barcelona km. 33,600 28805 Alcalá de Henares, Madrid, España
,
Tânia C.S.P. Pires
3   Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal
4   Laboratório Associado para a Sustentabilidade e Tecnologia em Regiões de Montanha (SusTEC), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Braganca, Portugal
,
Ricardo C. Calhelha
3   Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal
4   Laboratório Associado para a Sustentabilidade e Tecnologia em Regiões de Montanha (SusTEC), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Braganca, Portugal
,
Eva María Domínguez Martín
1   CBIOS – Universidade Lusófona’s Research Center for Biosciences & Health Technologies, Campo Grande 376, 1749-024 Lisbon, Portugal
2   Universidad de Alcalá de Henares. Facultad de Farmacia, Departamento de Ciencias Biomédicas (Área de Farmacología; Nuevos agentes antitumorales, Acción tóxica sobre células leucémicas. Ctra. Madrid-Barcelona km. 33,600 28805 Alcalá de Henares, Madrid, España
,
Ana María Díaz-Lanza
2   Universidad de Alcalá de Henares. Facultad de Farmacia, Departamento de Ciencias Biomédicas (Área de Farmacología; Nuevos agentes antitumorales, Acción tóxica sobre células leucémicas. Ctra. Madrid-Barcelona km. 33,600 28805 Alcalá de Henares, Madrid, España
,
Miguel Vilas-Boas
3   Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal
4   Laboratório Associado para a Sustentabilidade e Tecnologia em Regiões de Montanha (SusTEC), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Braganca, Portugal
,
Soraia Falcão
3   Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal
4   Laboratório Associado para a Sustentabilidade e Tecnologia em Regiões de Montanha (SusTEC), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Braganca, Portugal
,
Patrícia Ríjo
1   CBIOS – Universidade Lusófona’s Research Center for Biosciences & Health Technologies, Campo Grande 376, 1749-024 Lisbon, Portugal
5   Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
› Institutsangaben
 
 

    Honey is a natural product with antioxidant and antimicrobial properties, has been used as a medicinal substance for centuries. Thisnatural product is mainly composed of a supersaturated solution of sugars, containing low water content and trace amounts of bioactive compounds. The flower source, climate, geographical origin, harvesting process and storage conditions are factors that influence the composition of the nectar, leading to significant changes in the chemical composition, physical properties, and bioactivity of honey1. Centauri Honey is harvested from bee colonies located in the wild Alps of Turkey´s mountainous region, approximately 2,500 meters above the Black Sea. The bees live in caves far from human settlements and other bees, and they have access to medicinal endemic blooms throughout the year.

    The aim of this work was to investigate the quality, physicochemical, nutritional parameters, and bioactivity of honey. The quality and physiochemical parameters was analysed by colour, moisture content, conductivity, pH and acidity, 5-HMF (5-Hydroxymethylfurfural), diastase index and proline. The nutritional values were determined assessing ash, protein content, sugars, carbohydrates and energy. The biological activity was evaluated through the antioxidant, antimicrobial activity (broth microdilution method) and cytotoxicity in cell lines (AGS, CaCo-2, MCF-7, NCI-H460, PLP2, HFF-2, and HaCat), and anti-inflammatory activity (using RAW 264.7 macrophages).

    Further studies are ongoing to scientifically validate the medicinal properties of Centauri Honey due to its exceptional chemical composition and thus to become an innovative Ingredient.


    Conflict of Interest

    The authors declare no conflict of interest.

    Publikationsverlauf

    Artikel online veröffentlicht:
    16. November 2023

    © 2023. Thieme. All rights reserved.

    Georg Thieme Verlag KG
    Rüdigerstraße 14, 70469 Stuttgart, Germany