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DOI: 10.1055/s-0043-1774013
Healing activity of the Viscum album eye drops
Extracts of the Viscum album (VA) plant gained several indications of use throughout history for the clinical improvement of patients. Among these indications is its healing activity, but the literature lacks reports about this feature. Fibroblasts and keratinocytes are directly involved in this context, and greater stimulation of these cells is beneficial to accelerate the healing of wounds. This work aims to verify the cell proliferation capacity of the Viscum album homeopathic eye drops at 6DH (1 x 10-6) potency after a lesion that mimics the corneal groove.
HaCat keratinocyte cells were treated with the VA 6DH (1 x 10-6) eye drops at an 8 µL/mL concentration. The plates were opened, and after 24 hours, a scratch ([Fig. 1: A and B]) was performed. Treatment was then added to each well. After 48 hours of incubation with the eye drops ([Fig. 1: C and D]), the plates were analysed to define the percentage of healed area (Fig. 1: Table 1) using the Image J software. Statistical analysis was performed using the Graph Prisma Version 9.5.0. Data were analysed for normality using the Shapiro-Wilk test. Subsequently, the Student's t-test was performed for comparison of results. After statistical analysis, data were considered normal (parametric) and demonstrated that the VA 6DH (1 x 10-6) eye drops provided more significant healing of the area (p=0.0071) compared to the control treatment (Fig. 1: Bottom right). The results indicate that the VA 6DH (1 x 10-6) eye drops may assist in the treatment of eye injury.
Publication History
Article published online:
16 November 2023
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