Pyridazines Part XXIII: [1] Efficient Arylation at Position 5 of the 6-Phenyl-(2H)-pyridazin-3-one System Using a Suzuki Cross-Coupling Reaction

Abstract

A highly efficient procedure for introducing aryl or heteroaryl rings at position 5 of the 6-phenyl-(2H)-pyridazin-3-one system using a Suzuki cross-coupling reaction has been developed in the search for new platelet aggregation inhibitors.

Key words

arylations - palladium - catalysis - pyridazin-3-ones

References

• 1a

  Part of this work was presented at the 7 ^th International Symposium on the Chemistry and Pharmacology of Pyridazines, Santiago de Compostela, Spain, September 2000.

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