An Efficient Synthesis of Dibenzocycloocta-4a,6a,-diene-5,11-diyne and its Precursors

Abstract

Two efficient syntheses of dibenzocyclooctadienediyne 1 were developed employing known reactions, which utilize commercially available reagents. Both methods are an improvement on known syntheses resulting in 41% and 43% overall yields. The latter method also offers an efficient synthesis of dibenzocyclooctatetraene 9, which is one of the key reagents now commercially unavailable.

dibenzocyclooctadienediyne - elimination - lithium - sonication

References

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