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Synthesis 2002(16): 2344-2346
DOI: 10.1055/s-2002-35222
DOI: 10.1055/s-2002-35222
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New YorkAn Expeditious One-Pot Synthesis of Thiiranes from α-Halo Ketones in Solvent-Free Conditions Using Microwaves
Further Information
Received
19 July 2002
Publication Date:
04 November 2002 (online)
Publication History
Publication Date:
04 November 2002 (online)
Abstract
Thiiranes are obtained in excellent yields and with high diastereoselectivity upon microwave irradiation of a mixture of α-haloketones, O,O-diethyl hydrogen phosphorodithioate and alumina-supported sodium borohydride in solvent-free conditions.
Key words
α-haloketones - thiiranes - stereoselective synthesis - microwaves - solvent free - alumina supported
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