A Facile Asymmetric Synthesis of Tetrahydroisoquinoline and Tryptoline Derivatives with a Quaternary Carbon Center at C(3)

Abstract

Optically active tetrahydroisoquinoline and tryptoline derivatives with a quaternary carbon center at C(3) were prepared from l-DOPA and l-tryptophan, respectively.

heterocycles - asymmetric synthesis - amino acids - axial chirality - Pictet-Spengler reaction

References

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