An Expeditious Synthetic Access to β-(Z)-[(1-Propynyl)amino]enones and β-[(Z)-(1-Propynyl)amino]enoates

David Gravestock; Martin C. Dovey

doi:10.1055/s-2003-37654

PAPER

An Expeditious Synthetic Access to β-(Z)-[(1-Propynyl)amino]enones and β-[(Z)-(1-Propynyl)amino]enoates

David Gravestock*, Martin C. Dovey
School of Chemical and Physical Sciences, University of Natal, Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa.
Fax: +27(33)260 5009; e-Mail: GravestockD@nu.ac.za;

Abstract

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Abstract

The silver nitrate promoted reaction of propargyl bromide with (Z)-4-amino-3-penten-2-ones and (Z)-3-amino-2-butenoates provides rapid access to β-(Z)-[(1-propynyl)amino]enones and β-[(Z)-(1-propynyl)amino]enoates respectively.

Key words

β-aminoenones - β-aminoenoates - ynamines - microwave-mediated synthesis

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References

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