Three New Cyclopentanoid Monoterpenes from Picrorhiza scrophulariiflora

Abstract

Three new cyclopentanoid monoterpenes, named piscrocins A (1), B (2) and C (3), were isolated from the roots of Picrorhiza scrophulariiflora (Scrophulariaceae). The structures of these new compounds were established by 1D and 2D NMR spectroscopic techniques (¹H-¹H COSY, HMQC, HMBC, and NOESY) in combination with X-ray crystallographic analysis.

References

• 1 The Chinese P harmacopoeia. The People’s Health Publishing House & The Chemical Industry Publishing House Beijing; 1995 Vol. 1: p 204
• 2 Xie P S. Study on the chemical constituents of Picrorhiza scrophulariiflora .  Zhongcaoyao. 1983;  14 (8) 5-8
• 3 Wang D Q, He Z D, Feng B S, Yang C R. Chemical constituents from Picrorhiza scrophulariiflora .  Acta Botanica Yunnanica. 1993;  15 83-8
• 4 Li J X, Li P, Tezuka Y, Namba T, Kadota S. Three phenylethanoid glycosides and an iridoid glycoside from Picrorhiza scrophulariiflora .  Phytochemistry. 1998;  48 537-42
• 5 Morota T, Nishimura H, Sasaki H, Chin M, Sugama K, Katsuhara T, Mitsuhashi H. Five cyclopentanoid monoterpenes from Rehmannia glutinosa .  Phytochemistry. 1989;  28 2385-91