Synthesis 2005(5): 787-790  
DOI: 10.1055/s-2005-861826
PAPER
© Georg Thieme Verlag Stuttgart · New York

ZnO/CH3COCl: A New and Highly Efficient Catalyst for Dehydration of Aldoximes into Nitriles Under Solvent-Free Condition

Mona Hosseini Sarvari*
Department of Chemistry, Faculty of Science, Shiraz University, Shiraz 71454, Iran
e-Mail: hossaini@chem.susc.ac.ir;
Further Information

Publication History

Received 27 September 2004
Publication Date:
14 February 2005 (online)

Abstract

A rapid and efficient synthesis of nitriles via dehydration from the corresponding aldoximes has been carried out in the presence of ZnO/CH3COCl as catalyst under solvent free conditions in 83-95% yields. The zinc oxide (ZnO) powder can be re-used upto three times after simple washing with CH2Cl2.

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CRC, Handbook of Tables for Organic Compound Identification, 3rd & 54th ed.