Six New Triterpenoid Saponins from the Root and Stem Bark of Cephalanthus occidentalis

Abstract

From the root and stem bark of Cephalanthus occidentalis L., a common American wetland species, six new triterpenoid saponins (1 - 6), together with 29 known compounds were isolated and identified. On the basis of spectroscopic analysis and chemical degradation, the structures of new compounds were elucidated as 3-O-β-glucopyranosylcincholic acid (1), cincholic acid 28-O-β-glucopyranosyl ester (2), 3-O-β-glucopyranosyl-(1→4)-β-fucopyranosylcincholic acid (3), 3-O-β-glucopyranosyl-(1→4)-β-fucopyranosylcincholic acid 28-O-β-glucopyranosyl ester (4), 3-O-β-glucopyranosylcincholic acid 28-O-α-arabinopyranosyl-(1→2)-β-glucopyranosyl ester (5), and 3-O-β-glucopyranosylquinovic acid 28-O-α-arabinopyranosyl-(1→2)-β-glucopyranosyl ester (6).

Key words

Cephalanthus occidentalis - Rubiaceae - new triterpenoid saponins - alkaloids

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