Synthesis 2005(15): 2482-2486  
DOI: 10.1055/s-2005-872090
PAPER
© Georg Thieme Verlag Stuttgart · New York

A Novel, Simple and Efficient Synthesis of Ferrocenyl Enones and Alkynols

Moran Sun, Qinghui Shi, Guosheng Huang*, Yongmin Liang, Yongxiang Ma
Department of Chemistry and State Key Laboratory of Applied Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
Fax: +86(931)8912582; e-Mail: hgs@lzu.edu.cn;
Further Information

Publication History

Received 7 March 2005
Publication Date:
21 July 2005 (online)

Abstract

A mild and efficient alkoxide-catalyzed addition of ferrocenylacetylene to diverse ketones and aldehydes is described. Some new propargyl alcohols containing ferrocenyl moieties were obtained by addition of ferrocenylacetylene to ketones. When aromatic aldehydes were used, trans-enones such as ferrocenyl chalcone derivatives were obtained in high yields via base-catalyzed addition-isomerization.