Synthesis 2006(1): 89-96  
DOI: 10.1055/s-2005-918435
PAPER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Orthogonally Protected Pyrrole Tricarboxylic Acid Derivatives: Versatile Building Blocks for Pyrrole-Containing Compounds

Carsten Schmuck*, Daniel Rupprecht, Christian Urban, Nicholas Walden
University of Würzburg, Institute of Organic Chemistry, Am Hubland, 97074 Würzburg, Germany
Fax: +49(931)8884625; e-Mail: schmuck@chemie.uni-wuerzburg.de;
Further Information

Publication History

Received 11 May 2005
Publication Date:
25 October 2005 (online)

Abstract

The large-scale synthesis of three new orthogonally protected pyrrole tricarboxylates 1-3 is described. Using different cleavage conditions, each of the three carboxylates can be set free selectively without affecting the others, making these pyrrole derivatives versatile synthetic building blocks for a wide range of applications in natural product or supramolecular chemistry.