Pyridinophanes as Two-Centre Phase-Transfer Catalyst for N-Alkylation Reaction

Abstract

The synthetic utility of water-soluble pyridinophanes 1 and 2 as an efficient two-centre phase-transfer catalyst for N-alkyl­ation of indoles, imidazole, benzimidazole and benzotriazole has been explored. Application of such pyridinophanes for the synthesis of various precyclophanes involving bis-N alkylation is also described.

Key words

phase-transfer catalyst - N-alkylation - pyridinophanes

References

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This work has been carried out in collaboration with Prof. D. Velmurugan, Department of Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, and will appear as a separate communication.