Abstract
Bioassay-guided fractionation of a crude ethanol extract from a Madagascar collection
of Schizolaena hystrix afforded the two new long-chain compounds, 3S -acetoxyeicosanoic acid ethyl ester (1 ) and 3S -acetoxydoeicosanoic acid (2 ), and the known long-chain compound 3S -acetoxyeicosanoic acid (3 ). In addition, the long-chain alcohol 1-hydroxydodecan-2-one (7 ), as well as the new flavonoid schizolaenone C (4 ) and the two known flavonoids diplacol (5 ) and 3′-prenylnaringenin (6 ) were isolated from a methanol extract of the same plant. Isolation and structure
elucidation of the novel compounds and the cytotoxicities of all the isolates are
reported.
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dkingston@vt.edu
