An Efficient Method for the α-Acetoxylation of Ketones

Abstract

α-Acetoxylation of ketones catalyzed by iodobenzene using 30% aqueous hydrogen peroxide and acetic anhydride as the oxidant is an effective and economical method for the preparation of α-acetoxy ketones. The reaction gave the products in good yields without the addition of acetic acid and water.

Key words

acetoxylation - iodobenzene - α-acetoxy ketones - iodine(III) catalysts - oxidation

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9

If the mixture was stirred at 40 °C for 4 h, it only needed to be cooled to r.t.