Intrauterine Coxsackie Virus, Group B Type 1, Infection: Viral Cultivation from Amniotic Fluid in the Third Trimester

Beatrice S. Strong; Stephen A. Young

doi:10.1055/s-2007-994407

American Journal of Perinatology, Table of Contents

Am J Perinatol 1995; 12(2): 78-79
DOI: 10.1055/s-2007-994407

ORIGINAL ARTICLE

Intrauterine Coxsackie Virus, Group B Type 1, Infection: Viral Cultivation from Amniotic Fluid in the Third Trimester

Beatrice S. Strong, Stephen A. Young

Departments of Pathology and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico

Abstract

ABSTRACT

We report a case that presents clear evidence of an intrauterine infection of twin fetuses with an enterovirus. The mother had signs and symptoms of chorioamniotitis at 34 weeks' gestation. Coxsackie virus, group B type 1 (CVB1), was cultured from amniotic fluid obtained by transabdominal amniocentesis when the membranes of both fetuses were still intact. Delivery occurred vaginally approximately 24 hours later, following spontaneous rupture of membranes. At birth, both twins showed signs of sepsis. Postpartum, CVB1 was recovered from the mother's cervix, and the newborns' cerebrospinal fluid, nasopharyngeal, and rectal swabs. The present significance of this case is discussed.

Keywords

Chorioamnionitis - enterovirus - Coxsackie virus - intrauterine infection

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