Eur J Pediatr Surg 2008; 18(4): 266-268
DOI: 10.1055/s-2008-1038363
Case Report

© Georg Thieme Verlag KG Stuttgart · New York

Immunohistochemical Findings in Rectal Duplication Mimicking Rectal Prolapse

M. G. Cortese1 , A. Pucci2 , R. Macchieraldo1 , M. G. Sacco Casamassima1 , F. Canavese1
  • 1Department of Pediatric Surgery, Regina Margherita Children's Hospital, Turin, Italy
  • 2Department of Anatomo-Pathology, Regina Margherita Children's Hospital, Turin, Italy
Further Information

Publication History

received October 12, 2007

accepted after revision December 19, 2007

Publication Date:
14 August 2008 (online)

Abstract

Alimentary tract duplications represent rare anomalies, with only 5 % occurring in the rectum. The variety in clinical presentation may lead to a delay in diagnosis or to incorrect and multiple surgical procedures. We report the clinical, histological and immunohistochemical characteristics of a rectal duplication occurring in a 3-month-old male with an unusual clinical presentation. Using routine histology and immunohistochemistry, the rectal duplication showed the diffuse presence of gastric mucosa with a characteristic immunophenotype (i.e., diffuse cytokeratin 7 positivity and scattered chromogranin immunoreactivity). As far as we know, this is the first report showing an immunohistochemical differentiation pattern of gastric lining in a rectal duplication. Our results, showing the presence of gastric mucosa, are suggestive of a possible origin from the embryonic foregut.

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Dr. Roberta Macchieraldo

Department of Pediatric Surgery
Regina Margherita Children's Hospital

Piazza Polonia 94

10126 Turin

Italy

Email: roberta.mac@tiscali.it

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