Synfacts 2008(3): 0317-0317  
DOI: 10.1055/s-2008-1042675
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

Oxidation of Alcohols Using Hydrotalcite-Supported Silver Nanoparticles

Contributor(s):Yasuhiro Uozumi, Yutaka Matsuura
T. Mitsudome, Y. Mikami, H. Funai, T. Mizugaki, K. Jitsukawa, K. Kaneda*
Osaka University, Japan
Oxidant-Free Alcohol Dehydrogenation Using a Reusable Hydrotalcite-Supported Silver Nanoparticle Catalyst
Angew. Chem. Int. Ed.  2008,  47:  138-141  
Further Information

Publication History

Publication Date:
21 February 2008 (online)


Hydrotalcite (HT) reacted with 5.0 mM aqueous solution of AgNO3 at 3 °C for 1 h to afford HT-supported Ag(I). The Ag(I) ions were reduced with hydrogen to give the Ag/HT catalyst (eq. 1). The oxidation (dehydrogenation) of various alcohols 1 without oxidant took place under Ar atmosphere in the presence of the Ag/HT catalyst to give the corresponding carbonyl compounds 2 with up to 99% conversion and chemo­selectivity (eq. 2). This catalyst was reused four times in the oxidation of 1-phenylethanol with no significant loss of activity and chemoselectivity.


In this paper, the HT-supported Ag nanoparticle was used as a highly selective catalyst for oxidation of various alcohols. The Ag/HT catalyst is superior to various hetero- or homogeneous catalysts, for example Ag/SiO2, Ag/TiO2, Pd/HT, Ru/HT, CP*Ir(PyOH). Generation of an equimolar amount of molecular H2 was observed as the alcohol oxidation proceeded.