Anti-Markovnikov Hydrogermylation of Alkenes via Lewis Acid Catalysis

Abstract

The direct hydrogermylation of alkenes under Lewis acid catalysis is reported. The use of borane B(C₆F₅)₃ as a catalyst allows for a mild, metal-free hydrogermylation of alkenes and concomitant reduction of ketones and aldehydes. Regardless of electronic biases, anti-Markovnikov hydrogermylation is observed in high yields. Moreover, the process is scalable and proceeds under mild conditions at room temperature.

Key words

organogermanes - hydrogermylation - Lewis acid - catalysis - anti-Markovnikov

Publication History

Received: 16 December 2022

Accepted after revision: 15 February 2023

Accepted Manuscript online:
15 February 2023

Article published online:
28 February 2023

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