Planta Med 2020; 86(05): 307-311
DOI: 10.1055/a-1088-9928
Biological and Pharmacological Activity
Reviews
Georg Thieme Verlag KG Stuttgart · New York

Sisymbrium officinale, the Plant of Singers: A Review of Its Properties and Uses

Maira Zorzan*
1   OU Endocrinology, Dept. Medicine (DIMED), University of Padova, Padova, Italy
,
Paolo Zucca*
2   Dipartimento di Scienze Biomediche, Università di Cagliari, Cagliari, Italy
,
Daniela Collazuol
1   OU Endocrinology, Dept. Medicine (DIMED), University of Padova, Padova, Italy
,
Stefania Peddio
2   Dipartimento di Scienze Biomediche, Università di Cagliari, Cagliari, Italy
,
Antonio Rescigno
2   Dipartimento di Scienze Biomediche, Università di Cagliari, Cagliari, Italy
,
Raffaele Pezzani
1   OU Endocrinology, Dept. Medicine (DIMED), University of Padova, Padova, Italy
3   AIROB, Associazione Italiana per la Ricerca Oncologica di Base, Padova, Italy
› Institutsangaben
Weitere Informationen

Publikationsverlauf

received 15. November 2019
revised 27. Dezember 2019

accepted 04. Januar 2020

Publikationsdatum:
04. Februar 2020 (online)

Abstract

Sisymbrium officinale (hedge mustard and formerly called Erysimum officinale) is a common plant in wild lands of Europe and Africa. It is also cultivated for its seeds and leaves to be used in salad or mustard. Sisymbrium officinale is useful not only in culinary preparations, but it also seems to possess interesting therapeutic properties, especially for throat diseases such as aphonia and hoarseness. For this reason, it is commonly called “herb of singers” (in Italian, “Erba dei cantanti”). Indeed a cup of Sisymbrium officinale infusion is frequently consumed by singers before artistic performance, even if its beneficial ability still needs to be scientifically demonstrated. Some preliminary data can be analyzed, but new efforts and resources should be devoted to study and investigate a plant with valuable therapeutic potential. This review summarizes the data available for Sisymbrium officinale.

* These 2 authors should be regarded as co-first authors.


 
  • References

  • 1 Pignatti S. Flora dʼItalia. Bologna: Edagricole; 1982
  • 2 Leclerc H. Précis de Phytothérapie. Paris: Elsevier Masson; 1983
  • 3 Rahman M, Khatun A, Liu L, Barkla BJ. Brassicaceae mustards: traditional and agronomic uses in Australia and New Zealand. Molecules 2018; 23: E231
  • 4 Di Sotto A, Vitalone A, Nicoletti M, Piccin A, Mazzanti G. Pharmacological and phytochemical study on a Sisymbrium officinale Scop. extract. J Ethnopharmacol 2010; 127: 731-736
  • 5 Karpozilos A, Pavlidis N. The treatment of cancer in Greek antiquity. Eur J Cancer 2004; 40: 2033-2040
  • 6 ClinicalTrials.gov. Clinical Trials. Available at: https://clinicaltrials.gov/ Accessed January 31, 2020
  • 7 Calcinoni O. Sisymbrium “Singersʼ plant” efficacy in reducing perceived vocal tract disability. J Otolaryngology-ENT Res 2017;
  • 8 Griffiths DW, Deighton N, Birch AN, Patrian B, Baur R, Stadler E. Identification of glucosinolates on the leaf surface of plants from the Cruciferae and other closely related species. Phytochemistry 2001; 57: 693-700
  • 9 Borgonovo G, Zimbaldi N, Guarise M, De Nisi P, De Petrocellis L, Schiano Moriello A, Bassoli A. Isothiocyanates and glucosinolates from Sisymbrium officinale (L.) Scop. (“the Singersʼ Plant”): isolation and in vitro assays on the somatosensory and pain receptor TRPA1 channel. Molecules 2019; 24: E949
  • 10 Fahey JW, Zalcmann AT, Talalay P. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. Phytochemistry 2001; 56: 5-51
  • 11 Guarise MB, Borgonovo G, Bassoli A, Ferrante A. Evaluation of two wild populations of hedge mustard (Sisymbrium officinale (L.) Scop.) as a potential leafy vegetable. Horticulturae 2019; 5: 13
  • 12 Blazevic I, Radonic A, Mastelic J, Zekic M, Skocibusic M, Maravic A. Hedge mustard (Sisymbrium officinale): chemical diversity of volatiles and their antimicrobial activity. Chem Biodivers 2010; 7: 2023-2034
  • 13 Carnat AF, Fraisse D, Carnat AP, Groubert A, Lamaison JL. Normalisation de lʼerysimum, Sisymbrium officinale L. Ann Pharm Fr 1998; 56: 36-39
  • 14 Zucca P, Bellot S, Rescigno A. The modern use of an ancient plant: exploring the antioxidant and nutraceutical potential of the Maltese mushroom (Cynomorium Coccineum L.). Antioxidants 2019; 8: E289
  • 15 Di Sotto A, Di Giacomo S, Toniolo C, Nicoletti M, Mazzanti G. Sisymbrium officinale (L.) Scop. and its polyphenolic fractions inhibit the mutagenicity of tert-butylhydroperoxide in Escherichia coli WP2uvrAR strain. Phytother Res 2016; 30: 829-834
  • 16 Quave CL, Plano LR, Pantuso T, Bennett BC. Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus . J Ethnopharmacol 2008; 118: 418-428
  • 17 Capuano E, Dekker M, Verkerk R, Oliviero T. Food as pharma? The case of glucosinolates. Curr Pharm Des 2017; 23: 2697-2721
  • 18 Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacol Res 2007; 55: 224-236
  • 19 Verhoeven DT, Goldbohm RA, van Poppel G, Verhagen H, van den Brandt PA. Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiol Biomarkers Prev 1996; 5: 733-748
  • 20 Di Sotto A, Di Giacomo S, Vitalone A, Nicoletti M, Mazzanti G. Antimutagenic thio compounds from Sisymbrium officinale . J Nat Prod 2012; 75: 2062-2068
  • 21 Attia IBZ, Zucca P, Marincola FC, Piras A, Rosa A, Chaieb M, Rescigno A. Chemical composition and antioxidant potential differences between Cynomorium coccineum L. Growing in Italy and in Tunisia: effect of environmental stress. Diversity (Basel) 2018; 10: 53
  • 22 Boni UP, Patri G. Le erbe: medicinali aromatiche cosmetiche. Milano, Italy: Fratelli Fabbri; 1976
  • 23 Politi MB, Braca A, Altinier G, Sosa S, Ndjoko KI, Wolfender JL, Hostettmann K, Jiménez-Barbero J. Different approaches to study the traditional remedy of “hierba del canto”, Sisymbrium officinale (L.) Scop. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas 2008; 7: 30-37
  • 24 Committee on Herbal Medicinal Products. Assessment report on Sisymbrium officinale (L.) Scop., herba. EMA/HMPC/280195/2013.